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Chemwiki

Reactivity of Ethers

Ethers are widely used as solvents for a variety of organic compounds and reactions, suggesting that they are relatively unreactive themselves. Indeed, with the exception of the alkanes, cycloalkanes and fluorocarbons, ethers are probably the least reactive, common class of organic compounds. The inert nature of the ethers relative to the alcohols is undoubtedly due to the absence of the reactive O–H bond.