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ChemWiki: The Dynamic Chemistry E-textbook > Organic Chemistry > Anhydrides > Reactions of Anhydrides > Acid Anhydrides react with alcohols to form esters

Acid Anhydrides react with alcohols to form esters

Introduction

Acid Anhydrides react with alcohols to form esters

General Reaction

Reactions of anhydrides use Pyridine as a solvent

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Example 1:
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Mechanism

1)   Nucleophilic Attack by the Alcohol

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2)  Deprotonation by pyridine

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3) Leaving group removal

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 4)  Protonation of the carboxylate

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Last Modified
22:32, 7 Nov 2013

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