III. Two-Step Sequential Reactions
- Page ID
- 23926
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When planning a sequential reaction, it is natural to gravitate toward elementary reactions that are rapid and occur in a highly predictable fashion; also, because a more complex structure is often the target in a synthetic reaction, forming a carbon–carbon bond is usually one of the goals of a sequential process. Since internal addition of a radical to a multiple bond often is both rapid and predictable and usually involves new carbon–carbon bond formation, many sequential reactions include at least one radical cyclization step; some contain more. Cyclization-cyclization, the first sequential reaction to be discussed, involves forming of two rings.