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IV. Transformation of Carbon-Centered Radicals

  • Page ID
    23944
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    Although every propagation step in a radical chain reaction involves conversion of one radi­cal into another, the potential for a synthetically useful reaction usually hinges on the trans­for­mation of a carbon-centered radical. Whether or not a transformation takes place depends on the relative rates for trans­forming and competing reactions. Because Bu3SnH or (Me3Si)3SiH often is present in a reaction mixture to provide a chain-carrying radical as well as to serve as a hydrogen donor after radical transformation has taken place, a common competing reaction for group migra­tion, radical cycli­zation, and radical addition is hydrogen-atom abstraction before transfor­mation occurs.


    This page titled IV. Transformation of Carbon-Centered Radicals is shared under a All Rights Reserved (used with permission) license and was authored, remixed, and/or curated by Roger W. Binkley and Edith R. Binkley.

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