V. Acyloxy Group Migration
- Page ID
- 24044
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Group migration in radical reactions follows one of two basic pathways. For aldehydo, cyano, and aryl groups, migration takes place by a sequence of elementary reactions consisting of cyclization and β-fragmentation steps. (An example of this type of reaction is shown in Scheme 8 of Chapter 10). Group migration in esters is governed by a different mechanism, one that has been the subject of considerable investigation. To follow the progress in understanding this reaction, it is useful to view the advances in mechanistic discovery in a chronological order.
