If you like us, please share us on social media.
The latest UCD Hyperlibrary newsletter is now complete, check it out.
Copyright (c) 2006-2014 MindTouch Inc.
This file and accompanying files are licensed under the MindTouch Master Subscription Agreement (MSA).
At any time, you shall not, directly or indirectly: (i) sublicense, resell, rent, lease, distribute, market, commercialize or otherwise transfer rights or usage to: (a) the Software, (b) any modified version or derivative work of the Software created by you or for you, or (c) MindTouch Open Source (which includes all non-supported versions of MindTouch-developed software), for any purpose including timesharing or service bureau purposes; (ii) remove or alter any copyright, trademark or proprietary notice in the Software; (iii) transfer, use or export the Software in violation of any applicable laws or regulations of any government or governmental agency; (iv) use or run on any of your hardware, or have deployed for use, any production version of MindTouch Open Source; (v) use any of the Support Services, Error corrections, Updates or Upgrades, for the MindTouch Open Source software or for any Server for which Support Services are not then purchased as provided hereunder; or (vi) reverse engineer, decompile or modify any encrypted or encoded portion of the Software.
A complete copy of the MSA is available at http://www.mindtouch.com/msa
In this chapter, we will extend our discussion, begun in chapter 6, of those organic reactions commonly known as 'nucleophilic substitutions'. In doing do, we will have an opportunity to consider in greater detail the various factors affecting the three main players in most organic reaction mechanisms: the nucleophile, the electrophile, and the leaving group. We will also see, for the first time, how stereochemical concepts are applied to the analysis of an organic reaction.
As we tackle this new and challenging chemistry, it is very important to keep in mind the central ideas that we learned in the acid-base chapter about electron density and how it is stabilized. At that time, we were talking about the breaking and forming of bonds to acidic hydrogens. Now, we will extend our discussion to reactions involving bonds between heteroatoms and carbon - but for much of what concerns us in this chapter, all of the fundamental ideas we’ve learned about electron density still apply!
An NSF funded Project